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SCIEX

API 2000

Precision OpticsIntroduced Produced 1998–SCIEX API 2000 family
Research Quality: 60% complete

Provisional entry — research in progress

This page was generated automatically from cited public sources and hasn't completed the full research pass yet. Every specification shown carries its source; more detail is added as research completes.

SCIEXAPI 2000
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  • Plate 01AB Sciex API 2000 Spectrometer [BOSTONIND] - 13433

    WWW.BOSTONIND.COM | Laboratory & Scientific Lab Equipment | Boston Industries, Inc.Watch on YouTube
  • Plate 02API 2000 Calculations: Part 2 - PEMY Consulting (Phil Myers)

    PEMY ConsultingWatch on YouTube

Produced

1998–

Vacuum

turbo-molecular-pumped[1]

Preceded by
First in line
This tool
API 2000
Succeeded by
API 7500
All related

What it is

The SCIEX API 2000 is a triple quadrupole mass spectrometer designed for liquid chromatography–tandem mass spectrometry (LC-MS/MS). The instrument was introduced in 1998 as a benchtop system. The API 2000 was developed by the AB Sciex joint venture between Applied Biosystems and MDS Sciex. The API 2000 belongs to the generation of SCIEX mass spectrometers that replaced the earlier cryopump-based API III platform with turbo-molecular-pumped vacuum systems.[1][2][4]

Where it fits in the process flow

General reference — not yet source-verified

The SCIEX API 2000 is typically coupled to a liquid chromatography (LC) system that separates compounds before mass spectrometric analysis. The LC system delivers the sample in a mobile phase to the ionization source of the mass spectrometer. Upstream processes include sample preparation and chromatographic separation. Downstream processes include data acquisition and analysis using software for quantification and identification of analytes.

Applications

General reference — not yet source-verified

The API 2000 is also used in food safety testing, proteomics research, and bioanalysis. The instrument supports a range of ionization techniques to accommodate different analyte polarities and sample matrices.

  • mass spectrometry

What do the numbers mean?

Power & electrical1

Power Requirements
2 separate 207 V minimum to 242 V maximum, 15 A grounded single phase circuit[3]
Accurate?

Vacuum & pumping1

pumping platform
turbo-molecular-pumped[1]
Accurate?

Dimensions & facilities2

Footprint (Width x Depth x Height)
104 cm x 50 cm x 64 cm[3]
Accurate?
Weight
111 kg (244 lb)[3]
Accurate?

Configuration & options6

form factor
benchtop[1]
Accurate?
instrument type
single and triple quadrupole mass spectrometer products[1]
Accurate?
Mass Range
m/z 5-1,800[3]
Accurate?
Dynamic Range
1 cps to 4x10^6 cps (pulse counting)[3]
Accurate?
Scan Speed
up to 2400 amu/sec[3]
Accurate?
Collision Cell
LINAC collision cell[3]
Accurate?

Vintage & configurations

  1. 1998platform evolution reference[1]

    In 1998, the cryopump API III platform began to be replaced with turbo-molecular-pumped single and triple quadrupole mass spectrometer products that evolved from the API 2000 and API 3000 to the API 7500 series.

  2. 1998-01-01Production start[2]

    Sales start

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What replaced it?

  • successorSCIEX API 7500The API 7500 series evolved from the API 2000 product line.source[1]
  • siblingSCIEX API 3000The source groups API 2000 and API 3000 together as products that evolved into the current API 7500 series.source[1]

What does it need to run?

Site utility requirements, footprint, and infrastructure needed to install and operate this tool. Sourced from public records.

  • pumping platformturbo-molecular-pumped[1]
  • Power Requirements2 separate 207 V minimum to 242 V maximum, 15 A grounded single phase circuit[3]

Where are the manuals?

Generated from public-source data on file. Enter your email to access — nothing is published; details are routed privately.

Not publicly documented

Field notes

No research found yet — worked with this tool? Share what you know.

Frequently asked questions

When was the SCIEX API 2000 introduced?

The SCIEX API 2000 was introduced in 1998.[2]

What type of mass analyzer does the API 2000 use?

The API 2000 uses a triple quadrupole mass analyzer.[5][2]

Which company manufactured the API 2000?

The API 2000 was manufactured by the AB Sciex joint venture between Applied Biosystems and MDS Sciex.[2][4][1]

Is the API 2000 a benchtop instrument?

Yes, the API 2000 is a benchtop system.[1]

Not publicly documented

The following facts about the API 2000 are absent from this record as of this revision. First-hand knowledge or a citation closes a gap; every submission is reviewed before publication.

  • No publicly documented variants, configuration options, or revision breakpoints of the API 2000 are on record.

    Answerable by: an OEM product catalog or an engineer who ordered or specified the tool

  • The control-system platform and OS era of the API 2000 are not on record.

    Answerable by: an engineer who operated it or OEM installation records

  • No publicly documented failure modes or field errata for the API 2000 are on record.

    Answerable by: a field service engineer, process engineer, or maintenance technician

  • The process node or technology generation of the API 2000 is not on record.

    Answerable by: an OEM datasheet or a fab qualification report

  • No publicly documented compatible parts, consumables, or accessories for the API 2000 are on record.

    Answerable by: an OEM parts catalog or a service engineer

No research found yet — worked with this tool? Share what you know.

Sources & citations

Sources (5)Every fact above is drawn from these public sources
  1. [1]en.wikipedia.orgen.wikipedia.orgen.wikipedia.org
  2. [2]mass-spec-capital.commass-spec-capital.commass-spec-capital.com
  3. [3]shop.labexchange.comshop.labexchange.com
  4. [4]API 2000 LC/MS/MS system AB Sciex (Applied Biosystems/MDS Sciex joint venture) - [MSC] Mass-Spec-Capital.com - The Mass Spectrometry Web Portalmass-spec-capital.commass-spec-capital.com
  5. [5]SCIEX API 2000 LC/MS/MS System – Spectralab Scientific Inc.spectralabsci.comspectralabsci.com
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Last updated Aug 13, 2026.

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