SCIEX
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Plate 01AB Sciex API 2000 Spectrometer [BOSTONIND] - 13433
Plate 02API 2000 Calculations: Part 2 - PEMY Consulting (Phil Myers)
Produced
1998–
Vacuum
turbo-molecular-pumped[1]
The SCIEX API 2000 is a triple quadrupole mass spectrometer designed for liquid chromatography–tandem mass spectrometry (LC-MS/MS). The instrument was introduced in 1998 as a benchtop system. The API 2000 was developed by the AB Sciex joint venture between Applied Biosystems and MDS Sciex. The API 2000 belongs to the generation of SCIEX mass spectrometers that replaced the earlier cryopump-based API III platform with turbo-molecular-pumped vacuum systems.[1][2][4]
The SCIEX API 2000 is typically coupled to a liquid chromatography (LC) system that separates compounds before mass spectrometric analysis. The LC system delivers the sample in a mobile phase to the ionization source of the mass spectrometer. Upstream processes include sample preparation and chromatographic separation. Downstream processes include data acquisition and analysis using software for quantification and identification of analytes.
The API 2000 is also used in food safety testing, proteomics research, and bioanalysis. The instrument supports a range of ionization techniques to accommodate different analyte polarities and sample matrices.
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The SCIEX API 2000 was introduced in 1998.[2]
The API 2000 was manufactured by the AB Sciex joint venture between Applied Biosystems and MDS Sciex.[2][4][1]
Yes, the API 2000 is a benchtop system.[1]
The following facts about the API 2000 are absent from this record as of this revision. First-hand knowledge or a citation closes a gap; every submission is reviewed before publication.
No publicly documented variants, configuration options, or revision breakpoints of the API 2000 are on record.
Answerable by: an OEM product catalog or an engineer who ordered or specified the tool
The control-system platform and OS era of the API 2000 are not on record.
Answerable by: an engineer who operated it or OEM installation records
No publicly documented failure modes or field errata for the API 2000 are on record.
Answerable by: a field service engineer, process engineer, or maintenance technician
The process node or technology generation of the API 2000 is not on record.
Answerable by: an OEM datasheet or a fab qualification report
No publicly documented compatible parts, consumables, or accessories for the API 2000 are on record.
Answerable by: an OEM parts catalog or a service engineer
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Last updated Aug 13, 2026.
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