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Zeiss

880

Zeiss 880 family
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The Zeiss LSM 880 is a laser scanning confocal microscope. The LSM 880 can be configured with an Airyscan detector. The LSM 880 uses ZEN software for operation.[1][2][3]

Zeiss logo
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What it is

The Zeiss LSM 880 is a laser scanning confocal microscope. The LSM 880 is an inverted confocal microscope. The LSM 880 is a laser scanning microscope. The LSM 880 is a confocal microscopy system.[1][2][5][3]

The Zeiss LSM 880 is an inverted confocal microscope with Airyscan. The Zeiss LSM 880 is a confocal light microscope with Airyscan. The LSM 880 is an upright confocal microscope in some configurations.[4][1][3][5]

The LSM 880 is a laser scanning confocal microscope with Airyscan. The LSM 880 is a laser scanning confocal microscope with Airyscan FAST.[1][3][5]

How it works

The LSM 880 is a laser scanning microscope. Laser scanning microscopes raster a focused laser beam across the sample point by point and build an image by collecting the emission at each pixel. The Zeiss LSM 880 uses the ZEN software for operation. The ZEN software controls the lasers, scan parameters, and detection channels.[1][3][2][5]

The LSM 880 supports multiple detection methods including a multichannel detector and a GaAsP detector for photon counting. The LSM 880 includes an Airyscan detector for increased resolution and signal-to-noise. The Airyscan detector uses a hexagonal array of pinholes coupled to individual detector elements. The system also supports fluorescence correlation spectroscopy (FCS).[1][2]

Applications

The LSM 880 supports multidimensional experiments including time series, z-stacks, tile scans, and FRAP. The LSM 880 with Airyscan is also used for super-resolution imaging. The LSM 880 is used for fluorescence correlation spectroscopy (FCS) measurements.[1][2][5]

What do the numbers mean?

Optics & imaging5

Microscope Type
Laser scanning confocal microscope[1]
Accurate?
Detector Type
Airyscan detector (optional)[1]
Accurate?
Detector Type
GaAsP detectors[1]
Accurate?
Laser Source
Multiline: 405, 440, 458, 488, 514, 543, 561, 594, 633 nm[2]
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Laser Source
UV laser module: 355 nm[2]
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Control & software1

Software
ZEN 2 (black edition)[1]
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Configuration & options3

manual title
Zeiss 880 Inverted Confocal Manual[4]
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microscope type
inverted confocal[4]
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OEM
Zeiss[4]
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Vintage & configurations

Documented models & variants

DesignationGenerationVintageChangesSource
LSM 880 NLOEquipped with a multi-photon laser (NLO) for non-linear optics excitationmanualslib.com[2]
LSM 880 with AiryScan FASTFAST version of Airyscanmanualslib.com[2]
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Where are the manuals?

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Not publicly documented

Field notes

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Frequently asked questions

What type of instrument is the Zeiss 880?

It is a confocal microscope.[4]

Where is the Zeiss 880 listed?

It appears in the Light Microscopy Core Facility’s microscopes and equipment area.[4]

Not publicly documented

The following facts about the 880 are absent from this record as of this revision. First-hand knowledge or a citation closes a gap; every submission is reviewed before publication.

  • No publicly documented production dates or lifecycle milestones (introduction, end of production, EOL) for the 880 are on record.

    Answerable by: OEM historical records or a trade-press announcement

  • The control-system platform and OS era of the 880 are not on record.

    Answerable by: an engineer who operated it or OEM installation records

  • No publicly documented failure modes or field errata for the 880 are on record.

    Answerable by: a field service engineer, process engineer, or maintenance technician

  • The process node or technology generation of the 880 is not on record.

    Answerable by: an OEM datasheet or a fab qualification report

  • No publicly documented compatible parts, consumables, or accessories for the 880 are on record.

    Answerable by: an OEM parts catalog or a service engineer

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Sources & citations

Sources (5)Every fact above is drawn from these public sources
  1. [1]manualslib.commanualslib.commanualslib.com
  2. [2]manualslib.commanualslib.commanualslib.com
  3. [3]ZEISS LSM 880 OPERATING MANUAL Pdf Download | ManualsLibmanualslib.commanualslib.com
  4. [4]microscopy.duke.edumicroscopy.duke.edumicroscopy.duke.edu
  5. [5]https://www.niehs.nih.gov/sites/default/files/research/atniehs/assets/docs/zeiss_lsm_880_inverted_confocal_microscope_with_airyscan_user_guide_508.pdfniehs.nih.govniehs.nih.gov
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Last updated Aug 13, 2026.

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