Malvern Panalytical

NS300

Metrology & Inspection Malvern Panalytical NS300 family

Research Quality: 60% complete

The Malvern Panalytical NS300 is a nanoparticle characterization instrument. The Malvern Panalytical NS300 uses Nanoparticle Tracking Analysis to measure nanoparticles in liquid. The Malvern Panalytical NS300 supports size distribution, concentration, and fluorescence measurements.^[1]^[2]^[3]

NS300 — cnfusers.cornell.edu — Fig. 01NS300cnfusers.cornell.edu^[1]

Plate 01Easy-to-use, reproducible platform for nano-particle characterisation - The NS300 from Malvern
AZoNetworkWatch on YouTube
Plate 02NanoSight NS300 basic training
Materials Characterisation & Fabrication PlatformWatch on YouTube

Power

100-240V, 50/60Hz^[5]

Optics

30 to 800 nm^[1]

What it is

The Malvern Panalytical NS300 is a nanoparticle characterization instrument. The Malvern Panalytical NS300 uses Nanoparticle Tracking Analysis to characterize nanoparticles in liquid and to measure particle size distribution and concentration. The Malvern Panalytical NS300 also supports fluorescence measurements.^[1]^[6]^[2]

How it works

General reference — not yet source-verified

Nanoparticle tracking instruments observe particles suspended in a liquid and derive size-related information from their motion. Nanoparticle tracking instruments are used as liquid-phase metrology tools for colloids, vesicles, and other nanoscale particle populations. Fluorescence-capable nanoparticle tracking instruments can distinguish labeled subsets within a mixed suspension.

Where it fits in the process flow

General reference — not yet source-verified

Nanoparticle characterization tools are analytical instruments rather than patterning or material removal tools. Nanoparticle characterization tools typically sit in characterization workflows after particle synthesis, dispersion preparation, separation, labeling, or collection steps. Nanoparticle characterization tools can also be used between development steps to compare changes in suspension behavior, aggregation state, or labeling response.

Applications

General reference — not yet source-verified

Nanoparticle tracking instruments are used to examine suspended particle populations in research and process-development work. Nanoparticle tracking instruments are suited to samples where particle-by-particle observation is useful, including mixed populations and fluorescently labeled fractions.

Particle size distribution and concentration measurement
Analyzing exosomes and vesicles shed from cells
Analyzing monodisperse and polydisperse samples

What do the numbers mean?

Power & electrical1

Power input: 100-240V, 50/60Hz^[5]

Optics & imaging11

Particle size range: 30 to 800 nm^[1]
Laser wavelength: 532 nm^[1]
Microscope magnification: 20X^[1]
Camera frame rate: 30 frames per second^[1]
Analysis range: 30 to 800 nm^[1]
Nanoparticle tracking analysis range: 10 nm to 2000 nm, depending on instrument configuration and sample type^[3]
Laser wavelength: 532 nm laser available for fluorescence measurements^[1]
Camera: 20X magnification microscope and camera; camera takes 30 frames per second^[1]
Laser class: Class 1 laser device; contains a Class 3B laser inside the laser module^[3]
Laser modules: Interchangeable laser modules^[2]
Camera type: High sensitivity sCMOS camera^[5]

Control & software2

Temperature control: Fully programmable using the NTA software^[3]
Interface: USB 2.0 input/output; Firewire B output^[5]

Configuration & options7

Measurement technique: Nanoparticle Tracking Analysis (NTA)^[1]
Particle concentration range: 10^6 to 10^9 particles/mL^[1]
Temperature range: 20 to 50 C^[1]
Sample volume required: ~1 mL^[1]
Analysis range: 0.01 to 1 µm, depending on instrument configuration and sample type^[2]
Filter wheel: Motorized 6-position filter wheel^[2]
Filter wheel: Motorized filter disc can present up to six different fluorescent filters^[4]

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What does it need to run?

Site utility requirements, footprint, and infrastructure needed to install and operate this tool. Sourced from public records.

Power input100-240V, 50/60Hz^[5]

Where are the manuals?

Generated from public-source data on file. Enter your email to access — nothing is published; details are routed privately.

Not publicly documented

Field notes

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Frequently asked questions

What measurement method does the NS300 use?

The Malvern Panalytical NS300 uses Nanoparticle Tracking Analysis. The Malvern Panalytical NS300 characterizes nanoparticles in liquid by observing individual particles and measuring diffusion events.^[1]^[6]

What does the NS300 measure?

The Malvern Panalytical NS300 measures particle size distribution and concentration. The Malvern Panalytical NS300 also provides fluorescence mode for differentiation of labeled or naturally fluorescing particles.^[1]

Not publicly documented

The following facts about the NS300 are absent from this record as of this revision. First-hand knowledge or a citation closes a gap; every submission is reviewed before publication.

No publicly documented production dates or lifecycle milestones (introduction, end of production, EOL) for the NS300 are on record.
Answerable by: OEM historical records or a trade-press announcement
No publicly documented variants, configuration options, or revision breakpoints of the NS300 are on record.
Answerable by: an OEM product catalog or an engineer who ordered or specified the tool
The control-system platform and OS era of the NS300 are not on record.
Answerable by: an engineer who operated it or OEM installation records
No publicly documented failure modes or field errata for the NS300 are on record.
Answerable by: a field service engineer, process engineer, or maintenance technician
The process node or technology generation of the NS300 is not on record.
Answerable by: an OEM datasheet or a fab qualification report